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Welcome to the IMGC Portal

The IMGC Web Portal enables members of the international milk and lactation research communities to collaborate and accelerate the understanding of the biological processes underlying mammalian milk genomics, the biological products that result from milk and lactation genes, and the health traits that these biological processes and products confer to both, the mother and the infant.
Award Winners Announced

Award Winners Announced
IMGC 2010 Portal Content Development Award Winners Announced!

The International Milk Genomics Consortium (IMGC) has announced the winners of the 2010 Portal Content Development Awards. The purpose of these awards is to increase the available content on the IMGC Web Portal with a goal of accelerating the understanding of the biological processes underlying the genomics of mammalian milk. From nine proposals received, we are presenting awards to the following four applicants:

Daniela Barile, UC Davis.  Annotation and curation of the bovine milk oligosaccharides library by advanced mass spectrometry.

Christophe Lefevre, Deakin University.  MamExp (MammoXpressionist): an interactive gene expression browser interface for collaborative comparative lactation genomics.

Palaniappan Ramanathan, University of Colorado.  Role of miRNAs in mammary gland development and lactation.

Francina Sagaya, Agroscope Liebefeld-Posieux Station ALP.  Enrichment analysis of transcription factors in blood cells in response to ingestion of bovine milk by health adult humans.

Thanks to all of those who submitted proposals and congratulations to the winners!

 

 
New Research

New Research
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Cow, Mouse, and Human Milk and Lactation Genome Browsers
 This highly valuable data resource includes milk protein genes, development stage-specific mammary genes, milk trait QTLs, milk trait candidate genes, statistically significant clusters of milk and mammary genes, and mammalian orthologs (human, mouse, rat, dog, opossum, platypus) of the bovine milk and mammary genes.
MamExp: online retrieval of expression data across experiments and species
MamExp (MammoXpressionist): an interactive gene expression browser interface for collaborative comparative lactation genomics.
 The increasing use of high throughput gene expression microarray analysis in lactation research is rapidly producing a large compendium of results on the expression of genes in the mammary tissue of an accruing number of species (bovine, mouse, human, seal, wallaby, monotremes…). Comparison of data from different species provides new opportunities to better understand the function of genes in the mammary gland and may ultimately lead to increased potential for applications to enhanced lactation in dairy cattle. The storage of mammary gene expression data, usually provided in a data exchange portal, does not allow the direct retrieval of gene expression lists or the comparison of lactation results from independent experiments or species. We are developing on-line facilities for the interrogation of gene expression data series and the reciprocal interspecies mapping of genes to facilitate the retrieval and visualization of gene expression data and the comparison of experimental results. Here, we propose to expand the database to include new data made available through the IMGC portal or otherwise made available in gene expression depository and enhance the functionality by customizing query interfaces and simplifying data upload. These developments will result in the provision of on-line data storage and retrieval interfaces for the interrogation and visualization of gene expression data related to mammary physiology and, will enable a more interactive comparative approach for the collaborative curation and analysis of microarray data.

More Research...
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Milk's role in directing the infant microbiome
 This IMGC portal project disseminates B. infantis genes active on milk substrates encountered within the infant gut.
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An Integrated Lactome Dataset
 The collective set of genes that contribute to the production of milk may be referred to as the “lactome”. This dataset is derived from analysis of multiple inbred mouse strains. The data includes links to electronic databases that provide detailed annotation for each element.
Getting Started

The IMGC Web Portal can be navigated like an ordinary website. Before you start exploring, you may wish to:

  1. Register for an account (click here).

  2. Log in (like this).  (Video tutorials can be seen in the Flash Player, you can get it here for free).
  3. Add new content to your folder (like this).
  4. Share it with a friend or colleague (like this).
  5. Leave comments about someone's content (like this).
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