subject: formula

Colostrum Through a Cultural Lens

Colostrum Through a Cultural Lens

In the first hours and days after a human baby is born, mothers aren't producing the white biofluid that typically comes to mind when we think about milk. They synthesize a yellowish milk known as colostrum or "pre-milk." Colostrum is the first substance human infants are adapted to consume, and despite being low in fat, colostrum plays many roles in the developing neonate. Historically and cross-culturally, colostrum was viewed very differently than it is amongst industrialized populations today. Read More...

A Human Milk Oligosaccharide Protects Against Intestinal Infection and Inflammation

A Human Milk Oligosaccharide Protects Against Intestinal Infection and Inflammation

Sugars found in human milk, called human milk oligosaccharides (HMOs), have various protective effects against intestinal infections. A new study finds that the HMO 2'-fucosyllactose (2'-FL) protects against infection and inflammation caused by the pathogen Campylobacter jejuni. Read More...

From Bench to Bedside: Translating Milk Science at the Clinician-Patient Interface

From Bench to Bedside: Translating Milk Science at the Clinician-Patient Interface

Emerging empirical research from chemistry, microbiology, animal science, nutrition, pediatrics, and evolutionary anthropology is accelerating our understanding of the magic of milk. Understanding the context and experiences of mothers of different races highlights the persistence of health care deficits that perpetuate breastfeeding disparities. Read More...

Human Milk Lowers Risk of Retinopathy Among Preterm Infants

Human Milk Lowers Risk of Retinopathy Among Preterm Infants

Retinopathy of prematurity (ROP) is a common affliction of very young preterm infants that can lead to blindness. It occurs when the blood supply to the retina develops abnormally. In some cases, this problem is so severe it can cause the retina to detach from the back inner wall of the eye. Decades ago, medical researchers demonstrated a difficulty in the care of the tiniest preterm infants: supplying these infants with lots of oxygen improved their chances of survival, while at the same time increasing their risk of ROP. A recent meta-analysis, however, offers more straightforward advice to neonatal intensive care units: Providing human milk to a very young preterm infant—whatever amount is available—significantly reduces the risk of the disease. Read More...

Why Mothers Should Boost Their Vitamin D Intake

Why Mothers Should Boost Their Vitamin D Intake

A mother's milk is the finest food her baby can get, but it's not perfect—or so it seems. It has become clear in recent years that most infants don't get enough vitamin D from breast milk—not by a long shot. Does this mean breast milk is inherently flawed, by some quirk of nature? A new study refutes this common belief by demonstrating that breast milk can indeed provide babies with enough vitamin D if their mother cranks up her vitamin D intake by more than 10 times the currently recommended amount. Read More...

How Probiotic Bacteria Protect Against Allergy to Cow’s Milk

How Probiotic Bacteria Protect Against Allergy to Cow’s Milk

Whether it’s to nuts, cow’s milk, eggs, or some other food, food allergies have become increasingly common in recent decades. Allergy to cow’s milk is especially common, affecting up to 3% of children worldwide. There have been many recent efforts to treat cow’s milk allergy, and probiotics have looked particularly promising. Recent studies have shown that feeding infants formula supplemented with the probiotic Lactobacillus rhamnosus GG (LGG) results in higher rates of tolerance to cow’s milk compared to infants fed unsupplemented formula. Read More...

Success Stories

Success Stories

Anyone involved in healthcare in the United States has probably heard that breastfeeding rates among African American mothers are much lower than those of any other racial grouping. As it happens, breastfeeding initiation rose by 8% in the African American community between 2000 and 2008, but the aforementioned gap still didn’t narrow. Research into the topic tends to focus on why these women aren’t breastfeeding, with studies often emphasizing statistical results, sometimes based on narrowly worded questionnaires. Recently, however, a nurse named Becky Spencer turned this perspective on its head: she has sought to understand African American breastfeeding successes. Read More...

Children Who Avoid Cow’s Milk May Fall Short of Vitamin D

Children Who Avoid Cow’s Milk May Fall Short of Vitamin D

Rickets and vitamin D deficiency do not sound like 21st century issues. Yet nearly 100 years since the connection between the two was first identified, the U.S., Canada, and numerous other countries are facing a potential epidemic of vitamin D deficiency among children (1). The reasons for the resurgence are much the same as they were in the past: limited sunlight exposure and poor dietary intake of this essential nutrient. Vitamin D-fortified milk helped bring an end to the rickets epidemic in the early 1900s, and it remains the best dietary source of vitamin D for children today. However, a growing number of children do not drink cow’s milk. A handful of studies have found that children who avoid cow’s milk due to allergy, intolerance, or dietary preference for alternative milk beverages are at a greater risk for vitamin D deficiency (2-4). When coupled with medical advice to avoid the sun, these findings could help explain the increasing prevalence of vitamin D deficiency in otherwise healthy children. While scurvy may have gone the way of the pirate, rickets is still a modern concern. Read More...

Milk Protein Comparison Unveils Nutritional Gems for Human Infants

Milk Protein Comparison Unveils Nutritional Gems for Human Infants

As any new parent can tell you, human newborns are very needy—and for good reason. Born at an earlier developmental stage than their primate relatives, human infants must accomplish a great deal of fetal development (some say the equivalent of nine more months!) outside of the womb. Responsibility for this “fourth trimester” falls squarely on the shoulders of human breast milk, and so it is no surprise that decades of research have searched for attributes in human milk that support the unique developmental needs of human infants. While much of the focus has gone to milk fats and carbohydrates, a new study has turned the attention to milk proteins (1). Utilizing new methods in protein identification, Beck et al. present the most comprehensive human milk proteome (the list of the types and quantities of all proteins in milk) to date, as well as the first milk proteome for a nonhuman primate, the rhesus macaque. Despite having less total protein than rhesus macaque milk, Beck et al. found that human milk has more than three times the types of proteins in rhesus milk and higher quantities of nearly every milk protein that the two species share. Their findings demonstrate that from digestion, to immunity, to neurodevelopment, human infants get more of a boost from milk proteins than their primate cousins. Read More...

Infection-Fighting Formula

Infection-Fighting Formula

There is a plethora of ways in which the composition of infant formula differs from that of breast milk. For one, the latter has a far greater diversity of ingredients, which are still not exhaustively known. But there are also plenty of known constituents of breast milk that are absent from infant formula. One team of researchers is dedicated to figuring out the implications of adding one kind of missing ingredient in particular—milk fat globule membrane (MFGM)—on infants’ health and development. Recently, this group identified some benefits to infants’ abilities to cope with infections when the infant formula they consume contains this supplement [1]. Read More...