subject: HIV

Drugs to Prevent HIV Infection are Barely Present in Human Milk

Drugs to Prevent HIV Infection are Barely Present in Human Milk

The World Health Organization considers someone with more than a 3% chance of contracting HIV in the next year to have a “substantial” risk of infection. This is important because it is the cut-off for which the WHO recommends taking anti-retroviral drugs, like tenofovir, to reduce the odds of infection. Breastfeeding women in sub-Saharan Africa easily meet this risk threshold. But medical professionals are discouraged from offering the drug to these women because of WHO warning labels about potential adverse reactions in nursing infants. That advice may now change, paving the way for many more at-risk women to receive HIV prophylaxis. A new study shows that when infants consume human milk from a woman taking tenofovir in combination with emtricitabine, they are exposed to extremely low levels of The World Health Organization considers someone with more than a 3% chance of contracting HIV in the next year to have a “substantial” risk of infection. This is important because it is the cut-off for which the WHO recommends taking anti-retroviral drugs, like tenofovir, to reduce the odds of infection. A new study shows that when infants consume human milk from a woman taking tenofovir in combination with emtricitabine, they are exposed to extremely low levels of either drug.drug. Therefore, the infants’ likelihood of experiencing adverse reactions is virtually non-existent. Read More...

The Future of HIV, with Tenascin-C

The Future of HIV, with Tenascin-C

It has been two decades since breast milk researchers realized that some chemical details of their favorite liquid of inquiry are protective against HIV infection. The protection is far from complete, but it is evident in a statistical anomaly: more than 90% of infants exposed to HIV through the breast milk they drink—their mucosal membranes doused with the virus every few hours, for about two years—never catch it. Read More...