IMGC - At the Intersection of Life Science
J. Bruce German - UC Davis
The International Milk Genomics Consortium is built on three
overlapping principles: that mammalian milks are the products of
Darwinian evolution to be nourishing, protective and supportive of the
growth, health and survival of mammalian infants; that the tools of
genomics are building the capabilities to mine mammalian genomes for
the functions of the lactation-associated genes that emerged during
mammalian evolution; and that understanding the molecules, mechanisms,
actions and benefits to health of these lactation-associated genes will
lead to the development of a new generation of foods and food
ingredients providing health to consumers of all ages. Key developments
over the past years have positioned the IMGC to accelerate its
progress. The major project to sequence the bovine genome is nearing
completion and the annotation process has begun. This sequence
information will significantly impact the tools for translating genomic
information into other tools, particularly proteomics and metabolomics
of milk and lactation. Finally, the pending arrival of various
microbial genomes obtained from bacteria whose ability to metabolize
the unique molecules and structures of milk represent a newly
recognized target of milk components actions, is a genuine breakthrough
in the science of human health. The IMGC’s overall goal is to assemble
the genetic instructions for the molecules in milk that arose through
evolution, and to ultimately understand the basis for their production
in milk and the nutritional advantage that they provide. It is
abundantly clear that such a bold and ambitious goal cannot be achieved
in a single laboratory or even a single institution—it is the logical
goal of the world’s scientific researchers. The IMGC program to link
the world’s scientific community around the goal of understanding the
biological values of milk by housing the common set of information,
orchestrating a common set of research tools and hosting an annual
conference is a unique opportunity to build this scientific resource
together. This 4th IMGC meeting is the most exciting yet and promises
to establish the formal electronic portal as the leading resource for
milk research.

