IssueM Articles

Future Plastic: Biofilms Derived from Colostral Milk Proteins

We all know that plastics are bad for the environment, and there is ongoing research indicating they are harmful to humans as well. When microplastics—less than 5 mm in length—get into oceans and tributaries, they end up in the fish and plants that we may consume. But plastic is an integral part of our lives. Computers, cars, and many household appliances are, or include components made of, plastic. Medical equipment like syringes, gloves, and the little plastic filters that go over thermometers for each new patient are one-time use items that help ensure good hygiene. And, of course, much of the food we buy is wrapped in plastic for both convenience as well as protection from contamination. In fact, it’s hard to imagine giving up the assurances that plastic can provide us when it comes to keeping our food safe. But advances in the development of milk protein-based edible films may soon make those wrappers not only less wasteful but even beneficial to our health, thus letting us have our cake and safely eating it, too.

Chew on This: Softer Diets of Preindustrial Dairy Farmers Influenced the Shape of Their Skull

The human family tree has an extinct genus that is remarkable for their massive jawbones, molars, and cranial crests (picture a bony mohawk). All of these anatomical features are proposed adaptations to the tough, fibrous diet of genus Paranthropus; hard and chewy diets require large chewing muscles, which in turn require larger jaw and cranial bones (and crests!) for points of attachment.

Human Milk Reduces Gut Inflammation after Bone Marrow Transplant

The human newborn’s gastrointestinal (GI) tract is immature and heavily reliant on components from human milk to successfully adapt to the novel challenges of life outside of the uterus. Recent research has highlighted the important role of milk’s bioactive components in establishing a healthy gut microbiome. Starting life off with the right mix of bacteria in the GI tract is essential not only for the development of the gut but also for mucosal immunity. It is so essential, in fact, the gut microbiome has been referred to as an ancillary immune organ.

Cheese May Be Good for Blood Circulation

Cheese is much more than just food. It is a part of the compelling story of ancient and modern human civilization. The huge range of cheeses today reflects the diversity of human taste and history. Cheese types also became a metaphor for public opinion. As Charles de Gaulle frustratingly said, “How can you govern a country (France), which has 246 varieties of cheese.” Adding to this impressive résumé of achievements, investigators recently demonstrated that hard cheese may also be good for blood circulation in older adults.

Cows May Go Green

It’s a tough gig being a cow. Productivity expectations for meat and milk are high, and at the same time, the cow gets a bad rap for belching a potent greenhouse gas, methane, which is a by-product of its digestion. Some people say it’s like driving a car very hard on a winding mountain road and then complaining about the car’s increased exhaust gas emissions. Reducing emissions and fuel consumption while maintaining performance is the golden ambition of car manufacturers. A similar goal is also true for the cow. People in many government agricultural agencies and the Food and Agriculture Organization (FAO) want the beef and dairy industries to use more productive cattle emitting less methane and using less feed i.e., increasing industry production efficiency while decreasing its environmental footprint. It’s a tall order seemingly resisted by the realities of cow biology, however recent ground-breaking research may have opened new opportunities to meet these ambitious aims.

Dairy Intake May Help Protect Against Functional Disability in the Elderly

Aging-related ailments can interfere with the daily life of the elderly. Older adults are at greater risk of diseases such as dementia or cardiovascular and orthopedic diseases. These diseases can contribute to functional disability—a decrease in physical, cognitive or emotional functioning that results from a health condition and adversely affects a person’s daily personal and social activities. Researchers have thus been looking for ways to decrease functional disability in the elderly.

Does Human Milk Composition Make the Infant Body Clock Tick?

Human beings have internal clocks. Locked in a room with no source of daylight nor regularly scheduled stimulation, our bodies cycle automatically through periods of slightly longer than 24 hours, sleeping and waking more or less as if the sun were rising and falling over a horizon that we could see. But we are not born this way. Instead, infants develop body clocks gradually. Researchers investigating this aspect of development have recently wondered how much human milk contributes to the process, in the knowledge that its levels of nutrients and hormones vary over the course of the day.

Milk Components Offer Safe Options for Targeted Drug Delivery

Milk has evolved through mammalian history as a soup of complex molecules that provide nutrients, as well as developmental and immunological support to infants. Some of these complex molecules have been naturally selected for their abilities to deliver bioactive compounds in such a way that the infant body can make use of them. This involves, for example, the ability to bind ions with positive and negative charges, such as iron and calcium ions, respectively—and protecting delicate compounds from stomach acids so they can be absorbed through the intestinal wall. In short, some of the soup of complex molecules in milk are ready-made nano-scale delivery units that could be harnessed by science to carry modern medicines into the body to precise locations.

MicroRNAs May Play a Key Role in Heat Stress Responses in Mammary Glands of Lactating Cows

A concern facing dairy farmers as the long, hot days of summer approach is the threat of heat stress in their cows. Experienced at temperatures above 80°F, heat stress affects growth and development as well as milk composition and volume. Heat stress is a major cause of low fertility in dairy cattle. It also increases susceptibility to metabolic disorders, mammary gland pathogens and mastitis. Compared with other livestock, cattle are unable to dissipate their heat load efficiently. Additional heat generated by the fermentation of food in the rumen compounds this problem. Cows’ sweating response is not highly effective, and the animals rely on respiration to cool themselves. Because of their inefficient response, cattle accumulate a heat load during the day that must be dissipated in cooler nighttime temperatures. In extreme weather conditions with overnight temperatures above 70°F, however, this doesn’t happen. Cattle experiencing increasing heat stress will stop feeding and become restless. They will then begin drooling and breathing more rapidly and with increased effort. They will also begin to group together, further exacerbating the problem. If not controlled, severe cases of heat stress will result in death. Economically, decreased milk yield and reproductive losses through hot summer months seriously affect the dairy industry. Increased occurrences of extreme weather conditions caused by ongoing global warming will only worsen these losses.

Antibody Type, Specificity, and Source Influence Their Survival in the Infant Gut

Maternal antibodies play an important role in protecting newborns from harmful pathogens. Antibodies known as immunoglobulins (Igs) are transferred from the mother’s placenta into the fetus, where they protect the infant while the infant’s immune system is still developing, Human milk also contains many different Igs, such as IgA, IgM, IgG, and secretory forms of IgA and IgM. Consuming human milk provides additional immune protection to infants and has been shown to reduce the risk of infectious diseases.